Very rare adrenal tumors

Metastases to the adrenal glands often appear completely asymptomatic and tend to be detected randomly during examinations of oncological patients. Nevertheless, they can have a major impact on further treatment as well as prognosis. Early recognition and the correct diagnostic-therapeutic approach are key.

Metastases to the adrenal glands are a fairly common finding in oncological patients, often bilateral, and their presence can fundamentally affect the further diagnostic and therapeutic procedure. In patients with an already diagnosed primary tumor, metastases to the adrenal glands occur in up to 20% of cases. Conversely, in patients without a prior diagnosis of malignancy, metastatic adrenal involvement is very rare (less than 0.5% of cases).

Název nádoru Charakteristika
Myelolipom Benigní nádor složený z tukové a hematopoetické tkáně
Hemangiom Vzácný benigní cévní nádor, často bez klinických příznaků
Schwannom Benigní nádor pocházející z nervové tkáně
Ganglioneurom Benigní nádor autonomního nervového systému, často asymptomatický
Ewingův sarkom Vzácný maligní nádor kostního původu, může se vyskytovat v nadledvině
Liposarkom Zhoubný nádor tukové tkáně, možný výskyt v retroperitoneu včetně nadledvin
Leiomyosarkom Zhoubný nádor hladké svaloviny, může postihnout nadledviny
Primární adrenální lymfom Velmi vzácný agresivní maligní nádor, často s bilaterálním postižením

Typical symptoms

Clinical manifestations varies according to the histological type of tumor. While benign lesions are often asymptomatic and found incidentally, some malignant forms present with systemic symptoms such as fatigue, weight loss, B-symptoms or manifestations of adrenal insufficiency (especially in bilateral lesions — e.g. primary adrenal lymphoma).

Not sure how best to proceed?

Every case is different. If you are not sure how to proceed further in a patient with a suspected adrenal tumor, please contact us. Together, we will assess the situation and recommend the next professional procedure — quickly, factually and in partnership.

contact us

or

call +420 233 555 000

Call Mon-Fri 7:30 — 19:00

Diagnostics

Anatomical imaging:

  • CT (computed tomography)
  • MRI (magnetic resonance imaging)

Functional imaging:

  • FDG PET is particularly beneficial for malignant lesions — e.g. Ewing's sarcoma, liposarcoma, leiomyosarcoma, primary adrenal lymphoma.

Biopsy:

Indication only in patients in whom further treatment or prognosis would be affected. It is always necessary first exclude pheochromocytoma.

Treatment options

  • Surgical resection — consider in localized lesions without signs of dissemination.
  • Ablation methods — radiofrequency ablation, cryoablation, especially when contraindicated in surgery.
  • Systemic oncology therapy — according to the histological type, the extent of the disease and the general condition of the patient.

Recommendations

  • Benign tumors (myelolipoma, hemangioma, schwannoma, ganglioneuroma): follow-up or surgical resection according to size/symptomatology.
  • Malignant tumors (Ewing's sarcoma, leiomyosarcoma, liposarcoma, primary adrenal lymphoma): radical resection, systemic treatment, staging using FDG PET.

Další onemocnění